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Lithium: Used to treat manic depression and other psychiatric disorders. Lithium aggravates psoriasis in about half of those with psoriasis who take it. However, people can ask their physicians about alternatives to lithium.
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Antimalarials: Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine has the lowest incidence of side effects.
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Inderal: This high blood pressure medication worsens psoriasis in about 25 percent to 30 percent of patients with psoriasis who take it. It is not known if all high blood pressure (beta blocker) medications worsen psoriasis, but they may have that potential. Sometimes other medications can be substituted.
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Quinidine: This heart medication has been reported to worsen some cases of psoriasis.
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Indomethacin: This drug is used to treat arthritis. It is a nonsteroidal anti-
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Allergies: Although unproven, some people suspect that allergies trigger their psoriasis.
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Diet: Although unproven, changing the diet has helped some people improve their psoriasis or avoid flares.
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Strep infection: May trigger guttate psoriasis.
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Weather: May make skin drier and more susceptible to a psoriasis outbreak.
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